• ERECTOGENIC ACTIVITIES AND MECHANISM OF ACTION OF AQUEOUS EXTRACT OF Ocimum gratissimum LEAF AND THYMOL ON PENILE TISSUE IN WISTAR RATS 

  SHITTU, Seyyid Alli-Sisse (2022-02)

  Erectile dysfunction is an increasing social and health concern. Relaxation of Corpus Cavernosum Smooth Muscle (CCSM) is required for penile erection. Thymol and thymol-containing plant, Ocimum gratissimum (OG), have ...
• ISOLATION OF STIGMASTEROL FROM Piptadeniastrum africanum (HOOK. F.) AND ITS MODULATORY EFFECT ON MITOCHONDRIAL-MEDIATED CELL DEATH IN LIVER AND COLONIC TOXICITY IN MICE 

  OLOJO, Folake Olayinka (2023-04)

  Hepatocellular and colonic damage are fatal outcomes arising from liver and colon toxicity. Modulation of mitochondrial-mediated cell death is a strategy in these diseases management. The use of synthetic drugs in the ...
• SEXUAL DIMORPHIC RESPONSE OF METABOLIC VARIABLES IN HIGH FAT DIET-INDUCED OBESITY IN WISTAR RATS ON LOW CALORIE DIET 

  DAVID, Ubong Edem (2023-02)

  Striking differences exist between men and women in lipid kinetics possibly due to sexual dimorphism in metabolism. However, the effect of prolonged intake of High Animal Fat Diets (HAFD), High Plant Fat Diets (HPFD) and ...
• ANTI-PLASMODIAL AND ANTI-INFLAMMATORY ACTIVITIES OF ETHANOL EXTRACT AND ETHYL ACETATE FRACTION OF Psidium guajava Linn LEAVES IN MICE AND RATS 

  AJAO, Mutiu Yombo (2023-07)

  Inflammation during malaria is a determinant for the progression of plasmodial infection that causes health burdens in humans. Emergence of parasite resistance, absence of dual antiplasmodial and anti-inflammatory ...
• NEUROBEHAVIOURAL AND BIOCHEMICAL EVIDENCE OF ANTIDEPRESSANT ACTIVITY OF TROXERUTIN IN MICE 

  SOWUNMI, Abimbola Adewale (2023-07)

  Depression is a debilitating neurological illness characterised by behavioural and neurochemical changes. Conventional antidepressants have poor efficacy, serious side effects and primarily target monoaminergic systems, ...
• EVALUATION OF BENEFICIAL EFFECTS OF LEVETIRACETAM AND CARBAMAZEPINE IN POST STROKE EPILEPSY 

  OGUNJIMI, Luqman Opeoluwa (2023-07)

  Post-stroke Epilepsy (PSE) has been identified as a significant clinical condition in stroke survivors affecting outcome, quality of life, and hospital cost. They are clinically underestimated without consensus for ...
• TRACE METALS, NEUROTRANSMITTERS AND OXIDATIVE STRESS MARKERS IN THE PATHOGENESIS OF AUTISM SPECTRUM DISORDERS AND CEREBRAL PALSY IN CHILDREN 

  AKINADE, Adekunbi Olufunke (2023-05)

  Autism Spectrum Disorders (ASD) and Cerebral Palsy (CP) are Neurodevelopmental Disorders (NDDs) with inconclusive genetic profiling. Currently, focus is on gene modulation in NDDs by environmental toxicants such as trace ...
• CYTOPROTECTION BY LEAF EXTRACT OF Tridax procumbens (LINN.) IN EMBRYONIC MOUSE, HEPG2 AND PANC-1 CELL LINES AND ARSENITEINDUCED TOXICITY IN RATS 

  SAMUEL, EKUNDAYO STEPHEN (2023-02)

  Pancreatic Ductal Adenocarcinoma (PDA) and Hepatocellular Carcinoma (HCC) are among the deadliest cancer types worldwide that are associated with arsenic intoxication. Current drugs used in cancer management show a lot ...
• CHEMOPREVENTIVE EFFECTS OF ROOT BARK EXTRACT OF C. PORTORICENSIS (BENTH.) IN N-NITROSO-N-METHYLUREA AND BENZO(A)PYRENE-INDUCED MAMMARY GLAND AND REPRODUCTIVE TOXICITY IN WISTAR RATS 

  ADEFISAN, ADEDOYIN OMOBOLANLE (2023-02)

  Breast cancer (BC) remains a disease with high morbidity and mortality. In Nigeria, BC represents about 23% of all cancer cases. Currently available chemotherapeutic interventions are associated with significant adverse ...
• BIOCHEMICAL EVALUATION OF PEPTIDE-BASED CERIUM OXIDE NANOPARTICLES ON STRUCTURE AND FUNCTION OF VITAL ORGANS IN ADULT RODENT 

  ADEBAYO, Olayinka Anthony (2023-02)

  The application of cerium oxide nanoparticle or nanoceria (CeO2NPs) in biomedical sciences as an antioxidant agent has gained prominence in recent times. Further medical application of CeO2NPs is still evolving. However, ...
• ANTIDIABETIC AND HEPATO-RENAL PROTECTIVE EFFECTS OF ETHYL ACETATE FRACTION OF METHANOL LEAF EXTRACT OF Solanum macrocarpon Linn IN STREPTOZOTOCIN-INDUCED DIABETIC MALE WISTAR RATS 

  ANJORIN, Oluwasegun Joseph (2023-12)

  Diabetes mellitus (DM), a metabolic disease, is becoming more prevalent globally. Solanum macrocarpon (Linn.) is traditionally used in the treatment of DM but there is paucity of information on the scientific evaluation ...
• NARINGENIN ATTENUATES NEUROBEHAVIOURAL DEFICITS AND BIOCHEMICAL PERTURBATIONS INDUCED BY CHRONIC HYPOXIC STRESS IN MICE 

  OLUGBEMIDE, ABIMBOLA SADIAT (2021-07)

  Hypoxic stress is known to induce depression, cognitive dysfunction and anxiety-related complications through the activation of oxidative and inflammatory signaling pathways. Thus, inhibition of these pathways might ...
• CYTOREMEDIATIVE POTENTIALS OF Vitellaria paradoxa (Gaertn. C.F) IN ARSENIC-INDUCED TOXICITY IN WISTAR RAT, HARWICH FRUIT FLY AND ITS ANTIPROLIFERATIVE ACTIVITY IN MCF-7 CELLS 

  OYIBO, AGHOGHO (2021-11)

  Arsenic, a class 1 carcinogen, is a major contaminant in drinking water globally. When ingested by humans and animals, it contributes to tissue damage through the mechanisms of oxidative stress and inflammation. Search ...
• PLUMBAGIN-INDUCED TESTICULAR MITOCHONDRIAL-DEPENDENT CELL DEATH AND INFERTILITY IN MALE WISTAR RATS 

  BELLO, ISAAC JAMES (2021-12)

  The opening of the mitochondrial Permeability Transition (mPT) pore is an important event in mitochondrial-mediated cell death. Plumbagin, the active principle in Plumbago zeylanica, induces cell death in rapidly ...
• NEUROBEHAVIOURAL AND HISTOMORPHOLOGICAL CHANGES IN THE HIPPOCAMPUS AND CEREBELLUM OF WISTAR RATS TREATED WITH ARTESUNATE AND AMODIAQUINE 

  POPOOLA, ABDULGAFAR NIYI (2021-12)

  Artemisinin-based Combination Therapy (ACT) is among the best chemotherapeutic options for malaria. Artesunate (AS) + Amodiaquine (AQ) is a commonly used ACT in Nigeria, having good efficacy but with side effects ...
• ANTIHYPERTENSIVE POTENTIAL OF AQUEOUS EXTRACT OF Peristrophe bivalvis (L.) MERR. LEAF ON NG-NITRO L-ARGININE METHYL ESTER-INDUCED HYPERTENSION IN MALE WISTAR RATS 

  ALUKO, ESTHER OLUWASOLA (2021-09)

  Hypertension is a major risk factor for cardiovascular diseases. Most antihypertensive drugs have been reported to effectively reduce blood pressure (BP), but they do not ameliorate end-organ damage associated with ...
• THE PROLIFERATION AND MIGRATION OF GRANULE CELLS IN THE CEREBELLAR CORTEX OF NEONATAL SWISS MICE FOLLOWING MATERNAL TRYPTOPHAN ADMINISTRATION 

  ONATOLA, OLUBUNMI AYOBAMI (2021-07)

  The External Granular Layer (EGL) of the cerebellar cortex is a region of proliferative cells which migrate to their last position in the internal granular cell layer of the cerebellum. Delay in the transit of cells from ...
• GENETIC DIVERSITY OF Striga hermonthica (DEL.) BENTH. WEEDS FROM NIGERIA AND KENYA, AND THE GENETIC RESPONSES OF SELECTED HOST MAIZE LINES 

  UNACHUKWU, NNANNA NNAMDI (2019-12)

  Striga hermonthica (SH) is a parasitic weed that attacks and significantly reduces the yield of maize in Africa. The genetic interactions responsible for resistance or susceptibility of hosts to the parasite and the ...
• MATERNAL ADMINISTRATION OF Citrus limon LINN. JUICE, OLEIC, PALMITIC AND STEARIC ACIDS REDUCE PLACENTAL EFFICIENCY AND FOETAL MORPHOMETRY IN WISTAR RATS 

  AHMED, Taofiqat Tosin (2021-06)

  Lipids are essential in pregnancy homeostasis. Their reduction is associated with reduced birth weight a major predisposing factor to diseases in adulthood. Citrus limon (lemon) Juice (CLJ) is used in folkloric medicine ...
• THEROLESOFEXCESSIODINEANDGOITROGENICFOODSINTHYROID FUNCTIONANDGLUCOSEHOMEOSTASISINWISTARRATS 

  ARIGI, QueenEizaBisi (2021-01)

  Iodineisessentialforthyroidhormonesynthesis.Excessiveconsumptionof goitrogenicfoodslikesoybeans(GlycinemaxLinnaeus)andcassava(Manihot esculenta Crantz)which are staple foods in WestAfrica can resultin hypothyroidism.I ...

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