Basic Medical Sciences: Recent submissions

Now showing items 21-40 of 50

ANTI-DIABETIC EFFECTS OF THE LEAF EXTRACT OF Parquetina nigrescens (AFZEL.) BULLOCK, PHYTOL AND SQUALENE IN ALLOXAN-INDUCED DIABETES IN MALE WISTAR RATS

ADEYOMOYE, OLORUNSOLA ISRAEL (2021-05)

Diabetes mellitus is a disorder with episodes of hyperglycaemia. Although, Parquetina nigrescens has been reported to reduce blood glucose, the mechanisms of its normoglycaemic effect have not been fully elucidated. ...
GENETIC DIVERSITY OF HEPATITIS C VIRUS AMONG BLOOD DONORS AND SYMPTOMATIC PATIENTS IN SOUTHWESTERN NIGERIA

SHENGE, JULIET ADAMMA (2019-03)

Hepatitis C virus (HCV) infection results in liver cirrhosis, hepatic failure or hepatocellular carcinoma (HCC). The virus exhibits extreme sequence variability, which has resulted in emergence of variants that are distributed ...
GENETIC DIVERSITY AND DRUG RESISTANCE PATTERNS OF HIV-1 ISOLATES FROM DELTA, ANAMBRA AND IMO STATES, NIGERIA

UDEZE, AUGUSTINE OKECHUKWU, (2019-03)

Human Immunodeficiency Virus (HIV) is characterized by high genetic diversity which affects diagnosis, transmission, disease progression, vaccine design, co-receptor usage, response to antiretroviral therapy and development ...
GENOTYPIC CHARACTERISATION OF HUMAN RESPIRATORY SYNCYTIAL VIRUS IN CHILDREN PRESENTING WITH RESPIRATORY TRACT INFECTIONS IN IBADAN, NIGERIA

OGUNSEMOWO, OLUKUNLE SEUN, (2019-04)

Human Respiratory Syncytial Virus (HRSV) is the most common viral cause of acute lower respiratory tract infections in infants and young children,however, effective vaccine is yet to be licensed for human use till date. ...
MOLECULAR EPIDEMIOLOGY AND SOME FACTORS ASSOCIATED WITH GENITAL HUMAN PAPILLOMAVIRUS INFECTION AMONG WOMEN IN OYO STATE, NIGERIA

NEJO, YEWANDE TOLULOPE, (2019-03)

Genital Human Papillomavirus (HPV) infection is a well-established causative agent of cervical cancer; a major cancer in most developing countries.Persistent infection with high-risk HPV, especially types 16 and 18 have ...
METHANOL EXTRACT OF Parquetina nigrescens (AFZEL.) BULLOCK LEAF AND SQUALENE AMELIORATE ARSENIC TRIOXIDE-INDUCED REPRODUCTIVE TOXICITY IN MALE WISTAR RATS

ADEDOTUN, Oore-oluwapo Iretioluwa (2021-02)

In Nigeria, the concentration of arsenic in ground water, which is the major source of drinking water, is high. Arsenic causes male reproductive dysfunction by inducing oxidative stress. Parquetina nigrescens leaf, ...
THE ROLE OF MONOAMINERGIC SYSTEMS IN ANXIOLYTIC AND ANTI-DEPRESSANT POTENTIALS OF METHANOL EXTRACT OF ARTOCARPUS ALTILIS FOSBERG IN LABORATORY MICE

AZUBUIKE, AJAH AUSTIN (2018-10)

Anxiety is described as a threat to psychological, physiological and behavioral state, while depression is a potentially life-threatening disorder that presents with decreased mood.Folkloric use of Artocarpus altilis ...
IN VITRO AND IN VIVO ACTIVITIES OF THE STEM BARK EXTRACT OF Anacardium occidentale LINN. ON GUT MOTILITY IN LABORATORY RODENTS

OMOLASO, BLESSING OLUWAGBAMILA (2019-04)

Diarrhoea is a disease characterised by gut smooth muscle dysfunction associated with increased motility. Anacardium occidentale (Ao) stem bark possesses strong anti-diarrhoeal effect; however the mechanism of this effect ...
PROTECTIVE MECHANISMS OF Oryza glaberrima VARIETIES ON INDOMETHACIN-INDUCED GASTRIC ULCERATION IN MALE WISTAR RATS

OLATUNJI, TEMILADE (2019-04)

Consumption of Oryza glaberrima (Nigerian brown rice) varieties has increased over the years due to its good nutritional values. Unlike polished rice which lacks bran and has been documented to possess ulcerogenic activities, ...
MODULATORY ACTIVITY OF QUERCETIN ON REPRODUCTIVE FUNCTIONS IN ALCOHOL-AND NICOTINE-TREATED MALE WISTAR RATS

AKINTAYO, Christopher Oloruntoba (2018-11)

Infertility is a prevalent health condition and 50% of its prevalence is related to male factor. Exposure to testicular toxicants such as Alcohol (A) and Nicotine (N) contributes to male infertility via induction of oxidative ...
ANTI-HYPERTENSIVE PROPERTIES AND MECHANISMS OF ACTION OF THE EXTRACT AND FRACTIONS FROM Persea americana MILL. LEAF IN RATS

BADEJO, JOSEPH AYOTUNDE (2018-11)

Hypertension is a chronic cardiovascular disease characterised by persistent, elevated arterial blood pressure. High cost and adverse effect burden of current antihypertensive therapies necessitate the need for alternative ...
PROTECTIVE EFFECTS OF CORCHORUS OLITORIUS LEAF EXTRACT AND FRACTIONS AGAINST ISOPROTERENOL-INDUCED ACUTE MYOCARDIAL INFARCTION IN WISTAR RATS.

ALABI, BABATUNDE ADEBOLA (2019-06)

Acute Myocardial Infarction (AMI) is a leading cause of death associated with Heart Failure (HF) worldwide. Oxidative stress, inflammation and apoptosis are important underlying pathogenesis of AMI, which are not target ...
EVALUATION OF THE PERFORMANCE OF HISTIDINE-RICH PROTEIN-2 BASED RAPID DIAGNOSTIC TESTSAND ALLELIC DIVERSITY OF PLASMODIUM FALCIPARUM GENES IN IBADAN, SOUTHWESTERN NIGERIA

FUNWEI, ROLAND IBENIPERE (2019-07)

Misdiagnosis of malaria exposes patients to drug pressure which may contribute to the emergence of anti-malarial drug resistance. The WHO recommends the use of malaria Rapid Diagnostic Tests (mRDTs) to improve malaria ...
PHAGOCYTIC MECHANISM AND ITS PLASMA MODULATORS IN PULMONARY TUBERCULOSIS PATIENTS ON ANTI-TUBERCULOSIS CHEMOTHERAPY AND ZINC SUPPLEMENT B

EDEM, VICTORY FABIAN (2019-07)

The progression of tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tuberculosis) from latent to drug-sensitive TB (DS-TB) or multi-drug resistant TB (MDR-TB) depends on factors including host-pathogen ...
INFLAMMATORY MARKERS IN MALE FARM WORKERS EXPOSED TO DICHLORVOS ORGANOPHOSPHATE PESTICIDE IN IBARAPA COMMUNITY, SOUTHWESTERN NIGERIA

YAQUB, SURAJUDEEN ADEBAYO, (2019-07)

The need for improved agricultural yield led to increased use of various pesticides, especially organophosphate chemicals because of non-persistence in the environment. Dichlorvos organophosphate pesticide (DOP) is ...
HUMORAL IMMUNE RESPONSES AND MICRONUTRIENT LEVELS OF Ascaris lumbricoides-INFECTED NIGERIAN CHILDREN ON ANTHELMINTHIC DRUG OR ORAL VACCINATIONS

AKINWANDE, KAZEEM SANJO (2019-07)

Intestinal helminth infection is associated with altered immune responses and micronutrient status in infected children. These alterations compromise vaccine efficacy of infected children. There is paucity of information ...
EFFECT OF METHYL JASMONATEON BENIGN PROSTATIC HYPERPLASIA INWISTAR RATS

AKANNI, OLUBUKOLA OYEBIMPE (2019-06)

Benign ProstaticHyperplasia (BpH) is a progressive age-related disease. Currentdrugs used in the management of BpH have limited efficacy and many adverse effects, necessitating a continuous search for better options. Methyl ...
AMELIORATIVE EFFECTS OF APIGENIN ON DEXTRAN SULPHATE SODIUM-INDUCED ULCERATIVE COLITIS AND HEPATOTOXICITY IN MALE AND FEMALE BALB/c MICE

OGUNGBE, BIMPE FOLASADE (2019-05)

Ulcerative colitis (UC), a multifactorial inflammatory bowel disorder, is on the increase globally and a major risk factor for colorectal cancer. Existing drugs for treatment of UC have adverse effects, hence current ...
MODULATORY EFFECTS OF Cajanus cajan LINN. LEAVES ON MITOCHONDRIAL-MEDIATED APOPTOSIS IN EXPERIMENTAL MURINE MODELS

ALAO, OLAJUMOKE OLUFUNLAYO (2019-06)

The opening of the Mitochondrial Membrane Permeability Transition (MMPT) pore causes cytochrome C release (CCR) which is a point of no return for apoptosis to take place. Some medicinal plants are known to induce MMPT ...
MODULATION OF MITOCHONDRIAL-MEDIATED APOPTOSIS IN THE HEART AND LIVER OF STREPTOZOTOCIN-INDUCED DIABETIC RATS BY QUERCETIN AND VITAMIN E

DANIEL, OLUWATOYIN OSINIMEGA (2019-06)

A major feature of Type 2 Diabetes Mellitus (T2DM) is tissue wastage, arising from excessive apoptosis. Excessive apoptosis could be a function of mitochondrial disorders in T2DM. Antioxidants, such as quercetin and Vitamin ...

Now showing items 21-40 of 50

Search DSpace

Advanced Search

Browse

All of DSpace
This Community
- By Issue Date
- Authors
- Titles
- Subjects

Recently added

Basic Medical Sciences: Recent submissions

Search DSpace

Browse

All of DSpace

This Community

My Account