Polycystic Ovary Syndrome (PCOS) is an endocrine disorder with a global prevalence of 5-10%
among women of reproductive age. Women with PCOS have a 2.7-fold increased risk of developing
ovarian and cervical cancers. ...
Alstonia boonei (AB) and Alstonia congensis (AC), belonging to the family Apocynaceae are different but
closely related species, indigenous to Africa. The two plants possess varied biological activities including ...
Acetylcholinesterase (AChE) and Prolyl endopeptidases (PEP) are involved in the catalytic hydrolysis of acetylcholine and cleavage of neuropeptides influencing the activity of the brain, leading to some symptoms of Alzheimer’s ...
Sickle Cell Disease (SCD) affects primarily black populations. There are few drugs
available for the management of SCD with deleterious side effects complicating the
condition. Although many plants including Cassia ...
Cancer is the second leading cause of death globally. Several chemotherapeutic agents
used for the treatment of cancer have many side effects. This necessitated a search for
new potent chemotherapeutic agents with high ...
Peptic ulcer is a gastrointestinal disorder affecting about four million people globally. Some
currently used anti-ulcer drugs have side effects such as central nervous system disorder and
depression. This necessitated ...
The search for new bioactive compounds from the wild often leads to conservation issues.
Plant tissue culture, a less destructive source of plant materials is a priority technique.
There is paucity of studies on ...
The incidence of multi-drug resistant cancer cells and the adverse effects associated with available chemotherapy have necessitated the search for new drug candidates. Several traditional healers in Africa utilise plants ...
Gastric ulcer results from persistent erosions and damage of the stomach wall. Ethnomedicinalsurvey revealed two plants, Securidaca longepedunculata(Polygalaceae, SL) and Luffa cylindrica (Cucurbitaceae, LC) among others ...
Malaria is the second leading cause of death from infectious diseases in Africa. The
global burden of malaria is increasing due to drug-resistant parasites and insecticideresistant
mosquitoes. Meliaceae has been known ...